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194034-61-2

194034-61-2 Structure

194034-61-2 Structure
IdentificationBack Directory
[Name]

6-Chloro-9-(3,5-di-O-acetyl-2-O-methyl-β-D-ribofuranosyl)-9H-purine
[CAS]

194034-61-2
[Synonyms]

9-(3',5'-Di-O-acetyl-2'-O-methyl-b-D-ribofuranosyl)-6-chloropurine
6-Chloro-9-(3,5-di-O-acetyl-2-O-methyl-β-D-ribofuranosyl)-9H-purine
6-Chloro-9-(3,5-di-O-acetyl-2-O-methyl-β-D-ribofuranosyl)-9H-purine
9H-Purine, 6-chloro-9-(3,5-di-O-acetyl-2-O-methyl-β-D-ribofuranosyl)-
[Molecular Formula]

C15H17ClN4O6
[MOL File]

194034-61-2.mol
[Molecular Weight]

384.77
Chemical PropertiesBack Directory
[Boiling point ]

536.5±60.0 °C(Predicted)
[density ]

1.59±0.1 g/cm3(Predicted)
[pka]

0.76±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

6-Chloro-9-(3,5-di-O-acetyl-2-O-methyl-β-D-ribofuranosyl)-9H-purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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