| Identification | Back Directory | [Name]
YU238259 | [CAS]
1943733-16-1 | [Synonyms]
YU238259
YU-238259;YU 238259
Benzamide, N-[2-(5-chloro-2-pyridinyl)ethyl]-4-[[[(4-methoxyphenyl)sulfonyl]amino]methyl]- | [Molecular Formula]
C22H22ClN3O4S | [MDL Number]
MFCD30532769 | [MOL File]
1943733-16-1.mol | [Molecular Weight]
459.95 |
| Chemical Properties | Back Directory | [density ]
1.323±0.06 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml | [form ]
A crystalline solid | [pka]
11.46±0.50(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
YU 238259 is an anticancer agent that inhibits DNA damage repair. It also sensitizes tumors cells to radiation. | [in vivo]
YU238259 (3 mg/kg, i.p.) inhibits the growth of BRCA2-deficient tumor xenografts in nude mice[1]. |
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