| Identification | Back Directory | [Name]
SM-19712 | [CAS]
194542-56-8 | [Synonyms]
SM19712 sodium
SM-19712 hydrate
4-chloro-n-[[(4-cyano-3-methyl-1-phenyl-1h-pyrazol-5-yl)amino]carbonyl]benzenesulfonamide sodium salt
4-Chloro-N-[[(4-cyano-3-methyl-1-phenyl-1H-pyrazol-5-yl)amino]carbonyl]benzenesulfonamide sodium salt hydrate | [Molecular Formula]
C18H15ClN5NaO3S | [MDL Number]
MFCD06798351 | [MOL File]
194542-56-8.mol | [Molecular Weight]
439.85 |
| Hazard Information | Back Directory | [Uses]
SM-19712 hydrate was used in studies to determine the effectiveness of ECE inhibition as a treatment option for Alzheimerμs disease. | [Biological Activity]
SM-19712 a sulfonylureid-pyrazole derivative is a potent and selective inhibitor of endothelin converting enzyme (ECE). It attenuates the effects of ischemic acute renal failure and reduces the inflammationtissue injury and vasoconstriction induced by dextran sodium sulfate in mouse colon.''Nonpeptidepotent and selective endothelin converting enzyme inhibitor. |
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| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
| Company Name: |
SIGMA-RBI
|
| Tel: |
800 736 3690 (Orders) |
| Website: |
www.sigma-aldrich.com |
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