ChemicalBook--->CAS DataBase List--->1948273-09-3

1948273-09-3

1948273-09-3 Structure

1948273-09-3 Structure
IdentificationBack Directory
[Name]

Acetic acid, 2-[3-(2-aminoethoxy)propoxy]-, 1,1-dimethylethyl ester
[CAS]

1948273-09-3
[Synonyms]

NH2-PEG2-CH2-Boc
tert-Butyl 2-(3-(2-aminoethoxy)propoxy)acetate
2-[3-(2-Aminoethoxy)propoxy]acetic acid tert-butyl ester
Acetic acid, 2-[3-(2-aminoethoxy)propoxy]-, 1,1-dimethylethyl ester
[Molecular Formula]

C11H23NO4
[MDL Number]

MFCD30741911
[MOL File]

1948273-09-3.mol
[Molecular Weight]

233.3
Chemical PropertiesBack Directory
[Boiling point ]

314.0±27.0 °C(Predicted)
[density ]

1.014±0.06 g/cm3(Predicted)
[solubility ]

DMSO: 150 mg/mL (642.95 mM)
[form ]

Oil
[pka]

8.82±0.10(Predicted)
[color ]

Colorless to yellow
[Water Solubility ]

Water: 20 mg/mL (85.73 mM)
Hazard InformationBack Directory
[Uses]

NH2-PEG2-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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