| Identification | Back Directory | [Name]
N-METHYL-N-(4-NITROBENZYL)AMINE HYDROCHLORIDE | [CAS]
19499-60-6 | [Synonyms]
N-METHYL-N-(4-NITROB
N-Methyl-4-nitrobenzylaMine
4-Nitro-N-methylbenzylamine
Methyl-(4-nitro-benzyl)-amine
N-METHYL-N-(4-NITROBENZYL)AMINE
N-Methyl-N-(4-nitrobenzyl)amineHCl
N-methyl-1-(4-nitrophenyl)methanamine
Benzenemethanamine, N-methyl-4-nitro-
N-METHYL-4-NITROBENZYLAMINE HYDROCHLORIDE
N-METHYL-N-(4-NITROBENZYL)AMINE HYDROCHLORIDE
Methyl[(4-nitrophenyl)Methyl]aMine hydrochloride
N-Methyl-1-(4-nitrophenyl)MethanaMine hydrochloride | [Molecular Formula]
C8H11ClN2O2 | [MDL Number]
MFCD06407995 | [MOL File]
19499-60-6.mol | [Molecular Weight]
202.64 |
| Chemical Properties | Back Directory | [Melting point ]
218 °C | [Boiling point ]
277.2±15.0 °C(Predicted) | [density ]
1.162±0.06 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [form ]
Solid | [pka]
8.86±0.10(Predicted) | [Appearance]
Brown to reddish brown Solid | [CAS DataBase Reference]
19499-60-6 |
| Hazard Information | Back Directory | [Synthesis]
GENERAL STEPS: To prepare N-methyl-4-nitrobenzylamine; 4-nitrobenzaldehyde (15.0 g, 99.3 mmol) and 40% aqueous methylamine (17 mL) in methanol (250 mL) were mixed for 15 min at 0 °C, followed by addition of sodium borohydride (3.77 g). The reaction mixture was stirred at room temperature for 2 hours and then concentrated. Water (50 mL) was added to the residue and extracted with dichloromethane (3 x 250 mL). The organic phases were combined, dried and concentrated to give the target product N-methyl-4-nitrobenzylamine. Yield 15.4 g, 94% yield.1H NMR (CDCl3) δ 8.10 (m, 2H), 7.43 (m, 2H), 3.79 (s, 2H), 2.39 (s, 3H).MS (AP+) m/e 167 (MH+). | [References]
[1] Patent: WO2008/4117, 2008, A1. Location in patent: Page/Page column 116
[2] Molecules, 2017, vol. 22, # 12, |
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