ChemicalBook--->CAS DataBase List--->195199-95-2

195199-95-2

Request For Quotation
195199-95-2 Structure

195199-95-2 Structure
IdentificationBack Directory
[Name]

3-METHYL-N-[(1R)-1-METHYL-3-(4-METHYL-1-PIPERIDINYL)PROPYL]-N-METHYLBENZENESULFONAMIDE HYDROCHLORIDE
[CAS]

195199-95-2
[Synonyms]

SB 258719
SB-258719 >=98% (HPLC)
SB 258719 HYDROCHLORIDE
Benzenesulfonamide, N,3-dimethyl-N-[(1R)-1-methyl-3-(4-methyl-1-piperidinyl)propyl]-
3-METHYL-N-[(1R)-1-METHYL-3-(4-METHYL-1-PIPERIDINYL)PROPYL]-N-METHYLBENZENESULFONAMIDE HYDROCHLORIDE
[Molecular Formula]

C18H30N2O2S
[MDL Number]

MFCD09971125
[MOL File]

195199-95-2.mol
[Molecular Weight]

338.51
Chemical PropertiesBack Directory
[Boiling point ]

463.6±55.0 °C(Predicted)
[density ]

1.075±0.06 g/cm3(Predicted)
[storage temp. ]

Desiccate at RT
[solubility ]

DMSO: 250 mg/mL (738.53 mM)
[form ]

Liquid
[pka]

9.36±0.10(Predicted)
[color ]

Light yellow to yellow
[InChI]

1S/C18H30N2O2S/c1-15-8-11-20(12-9-15)13-10-17(3)19(4)23(21,22)18-7-5-6-16(2)14-18/h5-7,14-15,17H,8-13H2,1-4H3
[InChIKey]

AGVNHDNTFYHZNL-UHFFFAOYSA-N
[SMILES]

CC1=CC=CC(S(N(C)[C@H](C)CCN2CCC(C)CC2)(=O)=O)=C1
Safety DataBack Directory
[WGK Germany ]

WGK 3
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Hazard InformationBack Directory
[Uses]

SB 258719 Hydrochloride is a useful intermediate.
[Biological Activity]

Selective 5-HT 7 receptor antagonist that displays > 100-fold selectivity over a range of other receptors. Reverses the hypothermic effect of 5-CT in mice following i.p. administration.
[in vivo]

SB 258719 (5-20 mg/kg; i.p.) significantly attenuates the 5-CT-induced hypothermia[2].

Animal Model:Male Swiss Webster mice (20-25 g)[2].
Dosage:5-20 mg/kg
Administration:I.p.
Result:Significantly attenuated the 5-CT-induced hypothermia.
[IC 50]

5-HT7 Receptor: 7.5 (pKi)
Spectrum DetailBack Directory
[Spectrum Detail]

3-METHYL-N-[(1R)-1-METHYL-3-(4-METHYL-1-PIPERIDINYL)PROPYL]-N-METHYLBENZENESULFONAMIDE HYDROCHLORIDE(195199-95-2)1HNMR
195199-95-2 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354 , +17819995354
Website: https://www.targetmol.com/
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
Website: https://www.targetmol.com/
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 821-50328103-801 18930552037
Website: www.chemicalbook.com/ShowSupplierProductsList13285/0_EN.htm
Company Name: EMMX Biotechnology LLC  
Tel: 888-539-0666
Website: www.emmx.com
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Tel: 021-61312847; 18021002903
Website: http://www.shyuanye.com
Company Name: Fan De(Beijing) Biotechnology Co., Ltd.  
Tel: 15911056312
Website: www.bio-fount.com
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
Tel: 18818260767
Website: http://www.chemegen.com
Company Name: Energy Chemical  
Tel: 021-58432009 400-005-6266
Website: http://www.energy-chemical.com
Company Name: cjbscvictory  
Tel: 13348960310 13348960310;
Website: https://www.weikeqi-biotech.com/
Company Name: Beijing Jin Ming Biotechnology Co., Ltd.  
Tel: 010-60605840 15801484223;
Website: http://www.jm-bio.com/
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310
Website: https://www.targetmol.cn/
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: Beijing Boorsen Biotechnology Co., Ltd  
Tel: 400-901-9800 18611424007
Website: www.bioss.com.cn/
Company Name: Sangon Biotech (Shanghai) Co.,Ltd.  
Tel: 400-821-026
Website: www.sangon.com
Company Name: Merck KGaA  
Tel: 21-20338288
Website: www.sigmaaldrich.cn
Company Name: Biosynth Biological Technology (Suzhou) Co Ltd  
Tel: 51288865780
Website: www.biosynth.com
Company Name: Shanghai Amole Biotechnology Co., Ltd.  
Tel: 18916360931 18916360931
Website: www.amole.com.cn/
Company Name: Absin Bioscience Inc.  
Tel: 021-38015121-8802
Website: http://www.absin.cn
Tags:195199-95-2 Related Product Information