| Identification | Back Directory | [Name]
ACPT-II | [CAS]
195209-04-2 | [Synonyms]
ACPT-II
ACPTII,ACPT II
(1R,3R,4S)-1-AMINOCYCLOPENTANE-1,3,4-TRICARBOXYLIC ACID
4-AMINO-1ALPHA,2ALPHA,4BETA-CYCLOPENTANETRICARBOXYLIC ACID
1,2,4-Cyclopentanetricarboxylic acid, 4-amino-, (1α,2α,4α)- | [Molecular Formula]
C8H11NO6 | [MDL Number]
MFCD08705256 | [MOL File]
195209-04-2.mol | [Molecular Weight]
217.176 |
| Chemical Properties | Back Directory | [Boiling point ]
440.4±45.0 °C(Predicted) | [density ]
1.651±0.06 g/cm3(Predicted) | [storage temp. ]
Desiccate at -20°C | [solubility ]
DMF: 5 mg/ml; DMSO: 0.25 mg/ml; PBS pH 7.2: 10 mg/ml | [form ]
A crystalline solid | [pka]
1.85±0.60(Predicted) |
| Hazard Information | Back Directory | [Uses]
ACPT-II is a metabotropic glutamate receptor agonist, which exerts neuroprotective effects against kainate-induced excitotoxicity in primary neuronal cell and the dorsal hippocampus of rats. | [Biological Activity]
Competitive metabotropic receptor antagonist (K b values are 115, 88 and 77 μ M at mGlu 1a , mGlu 2 and mGlu 4a respectively). |
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