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1952236-05-3

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1952236-05-3 Structure

1952236-05-3 Structure
IdentificationBack Directory
[Name]

MTX-211
[CAS]

1952236-05-3
[Synonyms]

MTX-211
CPD1541
MTX-211, >98%
MTX-211; MTX211; MTX 211;1952236-05-3
N-(2-chloro-5-(4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl)pyridin-3-yl)methanesulfonamide
Methanesulfonamide, N-[2-chloro-5-[4-[(3-chloro-4-fluorophenyl)amino]-6-quinazolinyl]-3-pyridinyl]-
[Molecular Formula]

C20H14Cl2FN5O2S
[MDL Number]

MFCD31620832
[MOL File]

1952236-05-3.mol
[Molecular Weight]

478.33
Chemical PropertiesBack Directory
[Boiling point ]

642.8±65.0 °C(Predicted)
[density ]

1.577±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : ≥ 100 mg/mL (209.06 mM)
[form ]

Solid
[pka]

5.61±0.50(Predicted)
[color ]

Light yellow to khaki
Hazard InformationBack Directory
[Uses]

MTX-211 (Mol 211) is a dual inhibitor of EGFR and PI3K with IC50 values of ＜100 nM. MTX-211 can be used for the research of cancer and other diseases[1].
[IC 50]

EGFR; PI3K
[References]

[1] Small molecule inhibitors of egfr and pi3k. WO 2016100347 A2
Spectrum DetailBack Directory
[Spectrum Detail]

MTX-211(1952236-05-3)1HNMR
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