| Identification | Back Directory | [Name]
IFLAB-BB F2124-0088 | [CAS]
195252-56-3 | [Synonyms]
IFLAB-BB F2124-0088
6-CHLORO-N4-PROPYL-4,5-PYRIMIDINEDIAMINE | [Molecular Formula]
C7H11ClN4 | [MDL Number]
MFCD07440144 | [MOL File]
195252-56-3.mol | [Molecular Weight]
186.64 |
| Chemical Properties | Back Directory | [Boiling point ]
340.8±42.0 °C(Predicted) | [density ]
1.309±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C(protect from light) | [pka]
2.73±0.10(Predicted) |
| Hazard Information | Back Directory | [Synthesis]
General procedure: A mixed solution of 5-amino-4,6-dichloropyrimidine (1.0 mmol), triethylamine (1.0 mmol), ethanol (4.3 mL) and n-propylamine (2.5 mmol) was placed in an autoclave reactor, heated to a specified temperature and kept for a period of time. After completion of the reaction, the volatile components were evaporated under reduced pressure and the crude product was purified according to a specific method to obtain the target compound 6-chloro-N4-propyl-4,5-pyrimidinediamine. | [References]
[1] European Journal of Medicinal Chemistry, 2018, vol. 151, p. 199 - 213
[2] Journal of Medicinal Chemistry, 1997, vol. 40, # 20, p. 3207 - 3216
[3] Patent: WO2014/75393, 2014, A1. Location in patent: Page/Page column 175
[4] Organic Letters, 2017, vol. 19, # 23, p. 6360 - 6363 |
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| Company Name: |
NovoChemy Ltd.
|
| Tel: |
021-31261262/ 49 (0)17662837245 |
| Website: |
www.novochemy.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|