| Identification | Back Directory | [Name]
2-(piperidin-4-yl)benzoic acid hydrochloride | [CAS]
1955554-64-9 | [Synonyms]
2-(piperidin-4-yl)benzoic acid hydrochloride | [Molecular Formula]
C12H16ClNO2 | [MDL Number]
MFCD08460728 | [MOL File]
1955554-64-9.mol | [Molecular Weight]
241.72 |
| Hazard Information | Back Directory | [Uses]
2-(Piperidin-4-yl)benzoic acid hydrochloride is a 4-aryl piperidine useful as a semi-flexible linker in PROTAC development for targeted protein degradation. Incorporation of rigidity into the linker region of bifunctional protein degraders may impact the 3D orientation of the degrader and thus ternary complex formation as well as optimization of drug-like properties. | [reaction suitability]
reagent type: linker |
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