| Identification | Back Directory | [Name]
rel-(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid | [CAS]
195704-72-4 | [Synonyms]
rel-(2R,3R,4S)-4-(1,3-Benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-3-pyrrolidinecarboxylic acid
3-Pyrrolidinecarboxylic acid, 4-(1,3-benzodioxol-5-yl)-1-[2-(dibutylamino)-2-oxoethyl]-2-(4-methoxyphenyl)-, (2R,3R,4S)-rel- | [Molecular Formula]
C29H38N2O6 | [MOL File]
195704-72-4.mol | [Molecular Weight]
510.62 |
| Hazard Information | Back Directory | [Uses]
A-127722 is A 2, 4-dialarylpyrrolidine-3-carboxylic acid ETA selective endothelin receptor (ET receptor) antagonist with IC50 value of 0.36 nM[1]. | [Definition]
ChEBI: Atrasentan is a member of pyrrolidines. | [storage]
Store at -20°C | [References]
[1] Winn M, et al. 2,4-Diarylpyrrolidine-3-carboxylic acids--potent ETA selective endothelin receptor antagonists. 1. Discovery of A-127722. J Med Chem. 1996 Mar 1;39(5):1039-48. DOI:10.1021/jm9505369 |
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BOC Sciences
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https://www.bocsci.com |
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