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1964503-35-2

1964503-35-2 Structure

1964503-35-2 Structure
IdentificationBack Directory
[Name]

Biotin-NH(PEG4-acid)2
[CAS]

1964503-35-2
[Synonyms]

Biotin-NH(PEG4-acid)2
N-Biotin-N-bis(PEG4-acid)
4,7,10,13,19,22,25,28-Octaoxa-16-azahentriacontanedioic acid, 16-[5-[(3aR,4R,6aS)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]-, rel-
[Molecular Formula]

C32H57N3O14S
[MDL Number]

MFCD30458057
[MOL File]

1964503-35-2.mol
[Molecular Weight]

739.87
Chemical PropertiesBack Directory
[Boiling point ]

907.2±65.0 °C(Predicted)
[density ]

1?+-.0.06 g/cm3(Predicted)
[pka]

3.97±0.10(Predicted)
Hazard InformationBack Directory
[Description]

N-Biotin-N-bis(PEG4-acid) is a biotinylation reagent that allows reaction with two amine-containing moiety to form stable amide bonds.
[Uses]

N-Biotin-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50]

PEGs
[References]

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
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