| Identification | Back Directory | [Name]
2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione | [CAS]
19667-37-9 | [Synonyms]
Rivaroxaban Impurity 120
N-(3-Chloro-2-hydroxypropyl)phthalimide
2-(3-Chloro-2-hydroxypropyl)isoindoline-1,3-dione
2-(3-Chloro-2-hydroxypropyl)-2H-isoindole-1,3-dione
1H-Isoindole-1,3(2H)-dione, 2-(3-chloro-2-hydroxypropyl)- | [Molecular Formula]
C11H10ClNO3 | [MDL Number]
MFCD00086198 | [MOL File]
19667-37-9.mol | [Molecular Weight]
239.65 |
| Chemical Properties | Back Directory | [Melting point ]
95-96.5 °C | [Boiling point ]
405.4±35.0 °C(Predicted) | [density ]
1.444±0.06 g/cm3(Predicted) | [storage temp. ]
Storage temp. 2-8°C | [pka]
13.25±0.20(Predicted) | [Appearance]
White to off-white Solid |
| Hazard Information | Back Directory | [Uses]
2-(3-Chloro-2-hydroxypropyl)-1H-isoindole-1,3(2H)-dione has been used in yeast biosynthesis of (S)-adrenergic β-blockers by stereoselective reduction of haloketones. It has also been used in a validated LC-?MS?/MS method for the determination of three genotoxic impurities in rivaroxaban drug substance. |
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Sigma-Aldrich
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https://www.sigmaaldrich.cn |
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