ChemicalBook--->CAS DataBase List--->19819-18-2

19819-18-2

19819-18-2 Structure

19819-18-2 Structure
IdentificationBack Directory
[Name]

AKOS 92543
[CAS]

19819-18-2
[Synonyms]

CL-300619
AKOS 92543
Antiproliferative agent-15
2-phenyl-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one
2-Phenyl-5,6,7,8-tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4(3H)-one
[1]Benzothieno[2,3-d]pyrimidin-4(1H)-one, 5,6,7,8-tetrahydro-2-phenyl-
[Molecular Formula]

C16H14N2OS
[MDL Number]

MFCD01663489
[MOL File]

19819-18-2.mol
[Molecular Weight]

282.36
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Uses]

Antiproliferative agent-15 is an thienopyrimidine derivated anticancer agent. Antiproliferative agent-15 shows antiproliferative activity against human colon (HCT116 and HCT15) and brain (LN-229 and GBM-10) cancer cell lines[1].
[References]

[1] Haneen Amawi, et al. Thienopyrimidine derivatives exert their anticancer efficacy via apoptosis induction, oxidative stress and mitotic catastrophe. Eur J Med Chem. 2017 Sep 29;138:1053-1065. DOI:10.1016/j.ejmech.2017.07.028
Spectrum DetailBack Directory
[Spectrum Detail]

AKOS 92543(19819-18-2)1HNMR
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