| Identification | Back Directory | [Name]
CARBOSTYRIL 124 | [CAS]
19840-99-4 | [Synonyms]
CARBOSTYRIL 7
Carbostyryl 7
Carbostyryl 124
CARBOSTYRIL 124
CARBOSTYRIL 124 99%
4-Methyl-7-aminocarbostyril
7-Amino-4-methyl-carbostyril
7-amino-4-methyl-2-quinolone
Carbostyril 124, laser grade
7-amino-4-methyl-2-quinolinone
7-Amino-4-methylquinolin-2(1H)
7-amino-4-methyl-2(1h)-quinolinon
7-AMINO-4-METHYL-2(1H)-QUINOLINONE
7-amino-4-methylquinolin-2(1H)-one
7-amino-4-methyl-1H-quinolin-2-one
7-amino-4-methylhydroquinolin-2-one
2-Hydroxy-4-methyl-7-aminoquinoline
7-AMINO-2-HYDROXY-4-METHYLQUINOLINE
7-Amino-4-methylquinoline-2(1H)-one
7-Amino-4-methyl-2-hydroxyquinoline
2(1H)-Quinolinone, 7-amino-4-methyl-
4-Methyl-7-amino-1,2-dihydroquinoline-2-one
Carbostyril 124 [7-AMino-4-Methyl-2-quinolinol]
7-amino-4-methyl-2(1H)-quinolinone(SALTDATA: FREE)
7-Amino-4-methyl-2(1H)-quinolinone, 7-Amino-4-methyl-2-hydroxyquinoline | [EINECS(EC#)]
243-363-2 | [Molecular Formula]
C10H10N2O | [MDL Number]
MFCD00134256 | [MOL File]
19840-99-4.mol | [Molecular Weight]
174.2 |
| Chemical Properties | Back Directory | [Appearance]
Off-White to Tan Solid | [Melting point ]
>275°C (dec.) | [Boiling point ]
417.6±45.0 °C(Predicted) | [density ]
1.223±0.06 g/cm3(Predicted) | [storage temp. ]
Refrigerator | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
11.45±0.70(Predicted) | [color ]
Off-White to Light Beige | [λmax]
350 nm | [InChI]
1S/C10H10N2O/c1-6-4-10(13)12-9-5-7(11)2-3-8(6)9/h2-5H,11H2,1H3,(H,12,13) | [InChIKey]
MJXYFLJHTUSJGU-UHFFFAOYSA-N | [SMILES]
CC1=CC(=O)Nc2cc(N)ccc12 | [EPA Substance Registry System]
2(1H)-Quinolinone, 7-amino-4-methyl-(19840-99-4) |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White to Tan Solid | [Uses]
Suitable as a laser dye | [Description]
Suitable as a laser dye. Dyes and metabolites. | [General Description]
Carbostyril 124 (CS124) is a chromophore that can be used as a laser dye for sensitization and optical detection. It acts as an antenna molecule that facilitates the light absorption and enhances fluorescence efficiency. | [Synthesis]
GENERAL PROCEDURE: Isophthalamide (1.0 g, 9.3 mmol) was added to ethyl acetoacetate (1.2 eq, 2-3.6 g) and the mixture was heated to reflux for 20 hours. After completion of the reaction, the mixture was poured into ice (100 g) and the precipitate was collected by filtration. Purification by silica gel column chromatography (100-200 mesh, eluent methanol/chloroform, 1:99 v/v) afforded 7-amino-4-methylquinolin-2(1H)-one. | [References]
[1] Medicinal Chemistry Research, 2013, vol. 22, # 11, p. 5227 - 5235
[2] Medicinal Chemistry Research, 2010, vol. 19, # 2, p. 193 - 209
[3] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 4, p. 1624 - 1638
[4] Bioorganic and Medicinal Chemistry, 2006, vol. 14, # 24, p. 8712 - 8728
[5] Journal of Medicinal Chemistry, 2016, vol. 59, # 4, p. 1648 - 1653 |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
36/37/38 | [Safety Statements ]
26-36 | [WGK Germany ]
3 | [TSCA ]
TSCA listed | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
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