19877-89-5

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19877-89-5 Structure

Identification	Back Directory
[Name] vincanol
[CAS] 19877-89-5
[Synonyms] vincanol Vincanolum (3α,14α,16α)-14,15-Dihydroeburnamenin-14-ol Eburnamenin-14-ol, 14,15-dihydro-, (3α,14β,16α)-
[EINECS(EC#)] 243-388-9
[Molecular Formula] C19H24N2O
[MDL Number] MFCD00868229
[MOL File] 19877-89-5.mol
[Molecular Weight] 296.412

Hazard Information	Back Directory
[Uses] Vincanol ((-)-Isoeburnamine) is a blocker of voltage-gated Na+ channels. Vincanol blocks Na+ currents with an IC50 value of 40 μM. Vincanol has neuroprotective effect[1].
[References] [1] Erdo SA, et al. Vincamine and vincanol are potent blockers of voltage-gated Na+ channels. Eur J Pharmacol. 1996 Oct 24;314(1-2):69-73. DOI:10.1016/s0014-2999(96)00542-0

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