| Identification | Back Directory | [Name]
(3RS)-N-Methyl-3-phenyl-3-[2-(trifluoroMethyl)-phenoxy]propan-1-aMine Hydrochloride(2-TrifluoroMethylisoMer of Fluoxetine Hydro-chloride) | [CAS]
199188-97-1 | [Synonyms]
N-ForMylfluoxetine
Fluoxetine IMpurity
Fluoxetine Impurity 6
Fluoxetine Hydrochloride Imp. (EP)
N-Methyl-N-[3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]formamide
Formamide, N-methyl-N-[3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]-
(3RS)-N-Methyl-3-phenyl-3-[2-(trifluoroMethyl)-phenoxy]propan-1-aMine Hydrochloride(2-TrifluoroMethylisoMer of Fluoxetine Hydro-chloride) | [Molecular Formula]
C18H18F3NO2 | [MOL File]
199188-97-1.mol | [Molecular Weight]
337.34 |
| Chemical Properties | Back Directory | [Boiling point ]
475.3±45.0 °C(Predicted) | [density ]
1.209±0.06 g/cm3(Predicted) | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Thick Oil | [pka]
-0.54±0.70(Predicted) | [color ]
Colourless |
| Hazard Information | Back Directory | [Description]
N-Formylfluoxetine is impuritie generated during the production of fluoxetine. Fluoxetine (Fluoxetine, trade name Prozac) is a drug developed by Eli Lilly and launched in 1987 for the treatment of depression. It can also be used to treat symptoms of alcoholism, headaches, migraines, anxiety, and obesity. | [Uses]
N-Formylfluoxetine is an impurity generated during the production process of fluoxetine, which can be used as a reference substance for pharmaceutical impurities. | [Synthesis]
Fluoxetine (154.7 mg, 0.5 mmol), and a stirrer were placed into the reaction tube, and after displacing the inert gas, DMF (193 μL, 2.5 mmol) was added and the reaction tube was sealed. The reaction tube was placed in an oil bath reactor at 150 °C for |
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