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199807-33-5

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199807-33-5 Structure

199807-33-5 Structure
IdentificationBack Directory
[Name]

Cyclo(Arg-Gly-Asp-D-Phe-Val) TFA
[CAS]

199807-33-5
[Synonyms]

Cyclo(Arg-Gly-Asp-D-Phe-Val) TFA
[Molecular Formula]

C28H39F3N8O9
[MOL File]

199807-33-5.mol
[Molecular Weight]

688.66
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[color ]

White to off-white
[Sequence]

Cyclo(Arg-Gly-Asp-{d-Phe}-Val)
Hazard InformationBack Directory
[Uses]

Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) (Cyclo(RGDfV) (TFA))is an integrin αvβ3 inhibitor. Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) has antitumor activity. Cyclo(Arg-Gly-Asp-D-Phe-Val) (TFA) can be used for the research of acute myeloid leukemia[1].
[storage]

Store at -20°C
[References]

[1] Shen ZH, et al. Targeting of the leukemia microenvironment by c(RGDfV) overcomes the resistance to chemotherapy in acute myeloid leukemia in biomimetic polystyrene scaffolds. Oncol Lett. 2016 Nov;12(5):3278-3284. DOI:10.3892/ol.2016.5042
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