| Identification | Back Directory | [Name]
1-(4-ethylphenyl)-3-phenylurea | [CAS]
200134-22-1 | [Synonyms]
INH14
1-(4-ethylphenyl)-3-phenylurea
Urea, N-(4-ethylphenyl)-N'-phenyl- | [Molecular Formula]
C15H16N2O | [MOL File]
200134-22-1.mol | [Molecular Weight]
240.3 |
| Chemical Properties | Back Directory | [Boiling point ]
296.4±19.0 °C(Predicted) | [density ]
1.185±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
DMSO:86.5(Max Conc. mg/mL);359.96(Max Conc. mM)
Ethanol:18.0(Max Conc. mg/mL);74.9(Max Conc. mM) | [form ]
Solid | [pka]
14.46±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
INH14 is an inhibitor of TLR2-mediated NF-kB activation. | [in vivo]
INH14 (5 μg/g, i.p. for 2 hours) reduces lipopeptide-induced inflammation in mice[1]. | Animal Model: | 8-week old, male, pathogen-free C57BL/6J mice[1] | | Dosage: | 5 μg/g, one hour before Pam2CSK4 injection | | Administration: | I.P. for 2 hours | | Result: | Decreased TNFα production in mice. |
| [IC 50]
IKKβ: 3.59 μM (IC50); IKKα: 8.97 μM (IC50) | [storage]
Store at -20°C |
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| Company Name: |
cjbscvictory
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| Tel: |
13348960310 |
| Website: |
https://www.weikeqi-biotech.com/ |
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