| Identification | Back Directory | [Name]
Methanone, (4-bromo-5-fluoro-1H-pyrrol-2-yl)(3,5-dichloro-2-hydroxyphenyl)- | [CAS]
2001602-07-7 | [Synonyms]
Methanone, (4-bromo-5-fluoro-1H-pyrrol-2-yl)(3,5-dichloro-2-hydroxyphenyl)- | [Molecular Formula]
C11H5BrCl2FNO2 | [MOL File]
2001602-07-7.mol | [Molecular Weight]
352.97 |
| Chemical Properties | Back Directory | [Boiling point ]
453.1±45.0 °C(predicted) | [density ]
1.871±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
5.50±0.48(predicted) |
| Hazard Information | Back Directory | [Uses]
Antibiofilm agent-9 (Compound 4) is a pyrrolomycin derivative with antibacterial activity. Antibiofilm agent-9 inhibits Bacillus anthracis with MIC of 0.031 μg/mL. Antibiofilm agent-9 exhibits antibiofilm activity with 84% biofilm inhibition (24 h, 8.0 μg/mL). Antibiofilm agent-9 exhibits a good pharmacokinetic characters in mouse model[1]. | [References]
[1] Li L, et al., Pyrrolomycins and methods of using the same. WO2017011725. |
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