| Identification | Back Directory | [Name]
1-phenylguanidine | [CAS]
2002-16-6 | [Synonyms]
Phenylguanidine
1-phenylguanidine
N-Phenylguanidine
Guanidine, N-phenyl-
phenyl guanidine phenyl guanidine | [EINECS(EC#)]
217-898-7 | [Molecular Formula]
C7H9N3 | [MDL Number]
MFCD00092876 | [MOL File]
2002-16-6.mol | [Molecular Weight]
135.166 |
| Chemical Properties | Back Directory | [Melting point ]
222 °C | [Boiling point ]
231.9±23.0 °C(Predicted) | [density ]
1.17±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [pka]
pK1:10.77(+1) (25°C) |
| Hazard Information | Back Directory | [Chemical Properties]
This product is a colorless solid, mp 66～67℃, insoluble in water, soluble in organic solvents such as benzene. | [Uses]
Phenylguanidine is used to prepare (4-Aminomethyl)phenylguanidine derivative, which is a nonpeptidic highly selective inhibitor of human urokinase. A series of substituted phenylguanidine compounds are selective inhibitors of urokinase. | [Enzyme inhibitor]
This guanidine salt (FW = 136.18 g/mol; CAS 2002-16-6) inhibits trypsin,
Ki = 72.5 μM and urokinase, or u-plasminogen activator. |
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