| Identification | Back Directory | [Name]
DECOYININE | [CAS]
2004-04-8 | [Synonyms]
a14
U-7984
decoyinin
DECOYININE
angustmycina
antibiotica14
Decoyinine (U-7984)
Decoyinine [AngustMycin A]
5,6-Psicofuranosenyladenine
Adenosine, 4',5'-didehydro-1'-C-(hydroxymethyl)-
9-(6-Deoxy-D-β-erythro-hex-5-en-2-ulofuranosyl)adenine
9-(6-deoxy-beta-d-erythro-hex-5-enulofuranosyl)-adenin
9-(6-deoxy-beta-d-erythro-hex-5-enulofuranosyl)adenine
9-(6-Deoxy-β-D-erythro-5-hexeno-2-furanulonosyl)-9H-purin-6-amine
9H-Purin-6-amine, 9-(6-deoxy-β-D-erythro-hex-5-en-2-ulofuranosyl)-
9-(6-deoxy-beta-d-erythro-hex-5-en-2-ulofuranosyl)-9h-purin-6-amin
9-(tetrahydro-3,4-dihydroxy-2-(hydroxymethyl)-5-methylene-2-furyl)-adenin
9-(tetrahydro-3,4-dihydroxy-2-(hydroxymethyl)-5-methylene-2-furyl)adenine
(2R,3R,4S)-2-(6-aminopurin-9-yl)-2-(hydroxymethyl)-5-methylideneoxolane-3,4-diol
(2R,3R,4S)-2-(6-aminopurin-9-yl)-5-methylene-2-methylol-tetrahydrofuran-3,4-diol
(2R,3R,4S)-2-(6-azanylpurin-9-yl)-2-(hydroxymethyl)-5-methylidene-oxolane-3,4-diol | [Molecular Formula]
C11H13N5O4 | [MDL Number]
MFCD00210855 | [MOL File]
2004-04-8.mol | [Molecular Weight]
279.25 |
| Chemical Properties | Back Directory | [Melting point ]
198-200℃ | [Boiling point ]
639.8±65.0 °C(Predicted) | [density ]
1.87±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: soluble | [form ]
A crystalline solid | [pka]
12.90±0.60(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Decoyinin, is a Xanthosine monophosphate (XMP) aminase inhibitor and GMP synthetase inhibitor. It can also be used to study the inhibition of cell wall synthesis, to inhibit RNA synthesis, to lower intracellular GTP levels in Streptococcus mutans. | [Definition]
ChEBI: Decoyinine is a member of 6-aminopurines. | [in vivo]
It is showed that Decoyinine (Angustmycin A) treatment hinders tumor growth in xenograft mouse model. Moreover, like GMPS activity, the effect of Decoyinine does not appear to be subtype specific as it impairs growth of xenografts from cells harboring NRASQ61R (SK-Mel-103) or BRAFV600E (SK-Mel-28) mutations[1]. |
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| Company Name: |
Lynnchem
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| Telephone: |
86-(0)29-85992781 17792393971 |
| Website: |
http://www.lynnchem.com/ |
| Company Name: |
NewCan Biotech Limited
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| Telephone: |
+86-571-86912261 19975279805 |
| Website: |
https://www.newcanbio.com/ |
| Company Name: |
Shanghai UCHEM Inc.
|
| Telephone: |
+86-18930848214 +86-021-56762820 |
| Website: |
http://www.myuchem.com/ |
| Company Name: |
Wuhan Topule
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| Telephone: |
+86-02787215551 19945035818 |
| Website: |
http://www.topule.com/ |
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