ChemicalBook--->CAS DataBase List--->200563-11-7

200563-11-7

200563-11-7 Structure

200563-11-7 Structure
IdentificationBack Directory
[Name]

uvarigrin
[CAS]

200563-11-7
[Synonyms]

uvarigrin
2(5H)-Furanone, 3-[(13S,15R)-13,15-dihydroxy-15-[(2R,5R)-tetrahydro-5-[(1R)-1-hydroxytridecyl]-2-furanyl]pentadecyl]-5-methyl-, (5S)-
[Molecular Formula]

C37H68O6
[MDL Number]

MFCD32202747
[MOL File]

200563-11-7.mol
[Molecular Weight]

608.93
Chemical PropertiesBack Directory
[Boiling point ]

741.3±35.0 °C(Predicted)
[density ]

1.008±0.06 g/cm3 (20 ºC 760 Torr)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[pka]

14.20±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

Uvarigrin, isolated from the roots of Uvaria calamistrata, induces tumor multidrug resistance cell apoptosis and triggers Caspase-9 activation[1][2].
[storage]

Store at -20°C
[References]

[1] Zhou GX, et al. Calamistrins A and B, two new cytotoxic monotetrahydrofuran annonaceous acetogenins from Uvaria calamistrata. J Nat Prod. 1999 Feb;62(2):261-4. DOI:10.1021/np980334q
[2] Li YF, et al. Induction of apoptosis of tumor multidrug resistance cell by uvarigrin and its mechanism. Yao Xue Xue Bao. 2006 Mar;41(3):252-6. PMID:16758998
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