Identification | Back Directory | [Name]
4-[4-[4-(AMINOIMINOMETHYL)PHENYL]-1-PIPERAZINYL]-1-PIPERIDINEACETIC ACID TRIHYDROCHLORIDE | [CAS]
201304-22-5 | [Synonyms]
GR1440533HCl GR 144053 trihydroch GR 144053 TRIHYDROCHLORIDE GR 144053 TRIHYDROCHLORIDE HYDRATE 4-[4-[4-(AMINOIMINOMETHYL)PHENYL]-1-PIPERAZINYL]-1-PIPERIDINEACETIC ACID TRIHYDROCHLORIDE 4-[4-[4-(aminoiminomethyl)phenyl]-1-piperazinyl]-1-piperidineacetic acid trihydrochloride hydrate | [Molecular Formula]
C18H30Cl3N5O2 | [MDL Number]
MFCD06798360 | [MOL File]
201304-22-5.mol | [Molecular Weight]
454.82 |
Hazard Information | Back Directory | [Uses]
GR 144053 Trihydrochloride is a glycoprotein IIb/IIIa (integrin αIIbβ3) receptor antagonist. Antithrombotic. | [Biological Activity]
A potent and selective platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist (IC 50 = 37 nM). Orally active and highly effective at inhibiting thrombus formation in vivo . |
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