| Identification | Back Directory | [Name]
Autocamtide-2-related inhibitory peptide, myristoylated | [CAS]
201422-04-0 | [Synonyms]
L-Leucine, N2-(1-oxotetradecyl)-L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-arginyl-L-arginyl-L-glutaminyl-L-α-glutamyl-L-alanyl-L-valyl-L-α-aspartyl-L-alanyl- | [Molecular Formula]
C78H142N22O20 | [MDL Number]
MFCD01076524 | [MOL File]
201422-04-0.mol | [Molecular Weight]
1708.1 |
| Chemical Properties | Back Directory | [density ]
1.35±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
3.40±0.10(Predicted) | [color ]
White to off-white | [Water Solubility ]
Soluble to 1 mg/ml in water | [Sequence]
{Myr}-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Ala-Val-Asp-Ala-Leu |
| Hazard Information | Back Directory | [Uses]
Autocamtide-2-related inhibitory peptide, myristoylated is the myristoylated Autocamtide-2-related inhibitory peptide. Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM[1]. | [IC 50]
CaMK II | [storage]
Store at -20°C | [References]
[1] Ishida A, et al. A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II. Biochem Biophys Res Commun. 1995 Jul 26;212(3):806-12. DOI:10.1006/bbrc.1995.2040 |
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