| Identification | Back Directory | [Name]
(2-[(Chlorocarbonyl)oxy]ethyl)trimethylsilane | [CAS]
20160-60-5 | [Synonyms]
Teoc-Cl
2-trimethylsilylethylchloroformate
2-(trimethylsilyl)ethyl chloromethanoate
2-(Trimethylsilyl)ethyl carbonochloridate
(2-[(Chlorocarbonyl)oxy]ethyl)trimethylsilane
2-(trimethylsilyl)chlorocarboxylic acid ethyl ester
Carbonochloridic acid, 2-(trimethylsilyl)ethyl ester | [Molecular Formula]
C6H13ClO2Si | [MDL Number]
MFCD17013450 | [MOL File]
20160-60-5.mol | [Molecular Weight]
180.7 |
| Hazard Information | Back Directory | [Physical properties]
bp 34 °C/1 mmHg;bp 42–43 °C/4 mmHg;
d 0.9944 g cm3. | [Uses]
2-(Trimethylsilyl)ethyl Chloroformate is a reagent used in the introduction of the trimethylsilylethoxycarbonyl (Teoc) protecting
group for amines or alcohols; activation of tertiary
amines for dealkylation or ring opening; starting material for alternative reagents for introduction of the trimethylsilylethoxycarbonyl protecting group. It participates in the reactions of Protection of Amines, Protection of Alcohols, Dealkylation or Ring Opening of Tertiary Amines, Synthesis of Alternative Teoc Reagents etc. | [Preparation]
Prepared from 2-(trimethylsilyl)ethanol
and phosgene. | [storage]
moisture sensitive; stable for three months under nitrogen at 0 °C |
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