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201608-17-5

201608-17-5 Structure

201608-17-5 Structure
IdentificationBack Directory
[Name]

NF-κB Control
[CAS]

201608-17-5
[Synonyms]

NF-κB Control
NF-.kappa.B Control
NAOYXUUPTUDXHE-YQTWEEOYSA-N
[Molecular Formula]

C123H215N33O30S
[MOL File]

201608-17-5.mol
[Molecular Weight]

2668.29
Chemical PropertiesBack Directory
[density ]

1.37±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 25 mg/ml; DMSO: 10 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 1 mg/ml
[form ]

A crystalline solid
[Sequence]

Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Gln-Arg-Asn-Gly-Gln-Lys-Leu-Met-Pro
Hazard InformationBack Directory
[Uses]

NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. It blocks the nuclear import of p105 in cells treated with activators of NF-κB signaling, including LPS and TNF-α. NF-κB control is a peptide that is identical in sequence to NF-κB inhibitor, except two essential, basic residues of the p105 NLS are substituted with non-basic amino acids. It is ineffective at blocking the activation of NF-κB signaling and is used as a negative control peptide.[Cayman Chemical]
[storage]

Store at -20°C
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