| Identification | Back Directory | [Name]
Atrolactamide | [CAS]
2019-68-3 | [Synonyms]
Atrolactamide
(-)-α-Methyl-L-mandelamide
(+)-α-Methyl-D-mandelamide
2-hydroxy-2-phenylpropanamide
2-hydroxy-2-phenyl-propanamide
2-hydroxy-2-phenyl-propionamide
[S,(-)]-α-Hydroxyhydratropamide
[R,(+)]-α-Hydroxyhydratropamide
Benzeneacetamide, α-hydroxy-α-methyl-
[R,(+)]-2-Hydroxy-2-phenylpropionamide
[S,(-)]-2-Hydroxy-2-phenylpropionamide | [Molecular Formula]
C9H11NO2 | [MDL Number]
MFCD00068938 | [MOL File]
2019-68-3.mol | [Molecular Weight]
165.19 |
| Chemical Properties | Back Directory | [Melting point ]
62.5-63.5 °C(Solv: benzene (71-43-2)) | [Boiling point ]
349.3±35.0 °C(Predicted) | [density ]
1?+-.0.06 g/cm3(Predicted) | [pka]
12.53±0.29(Predicted) |
| Hazard Information | Back Directory | [Uses]
Atrolactamide (M-144) is a potent anticonvulsant. Atrolactamide can be used for the research of epilepsy[1]. | [Definition]
ChEBI: Atrolactamide is a member of acetamides. | [Synthesis Reference(s)]
Journal of Medicinal Chemistry, 46, p. 2494, 2003 DOI: 10.1021/jm020546r
Tetrahedron Letters, 21, p. 1219, 1980 DOI: 10.1016/S0040-4039(00)71375-X | [References]
[1] Schenck HA,et al. Design, synthesis and evaluation of novel hydroxyamides as orally available anticonvulsants. Bioorg Med Chem. 2004 Mar 1;12(5):979-93. DOI:10.1016/j.bmc.2003.12.011 |
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Merck KGaA
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21-20338288 |
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www.sigmaaldrich.cn |
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CHEMICAL LAND21
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www.chemicalland21.com |
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