| Identification | Back Directory | [Name]
6,7-dimethylisatin | [CAS]
20205-43-0 | [Synonyms]
6,7-dimethylisatin
1H-Indole-2,3-dione, 6,7-dimethyl-
6,7-dimethyl-1H-indole-2,3-dione(SALTDATA: FREE) | [Molecular Formula]
C10H9NO2 | [MDL Number]
MFCD00047221 | [MOL File]
20205-43-0.mol | [Molecular Weight]
175.18 |
| Hazard Information | Back Directory | [Uses]
6,7-Dimethylisatin (compound 1l), an Isatin (HY-Y0265) analogue, is a potent MAO inhibitor with IC50s of 20.3 μM and 6.74 μM for MAO-A and MAO-B, respectively. 6,7-Dimethylisatin has the potential for depression, Alzheimer's disease and Parkinson's disease research[1]. | [IC 50]
MAO-A: 20.3 μM (IC50); MAO-B: 6.74 μM (IC50) | [References]
[1] Izak F Prinsloo, et al. The evaluation of isatin analogues as inhibitors of monoamine oxidase. Chem Biol Drug Des. 2023 Nov;102(5):1067-1074. DOI:10.1111/cbdd.14304 |
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