| Identification | Back Directory | [Name]
9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine | [CAS]
20227-41-2 | [Synonyms]
2'-FANA-Ar
Ara-2'-F-2'-dA
-4-fluoro-2-(hydroxymethyl)
2'-Deoxy-2'-fluoroarabinoadenosine
2'-Deoxy-2'-fluoro-beta-D-arabinoadenosine
6-AMino-purine-2'-fluoro-2'-deoxy arabineoside
9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine
9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine
9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine
9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-9H-purin-6-amine
(2R,3R,4S,5R)-5-(6-Amino-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol | [Molecular Formula]
C10H12FN5O3 | [MDL Number]
MFCD12911815 | [MOL File]
20227-41-2.mol | [Molecular Weight]
269.23 |
| Chemical Properties | Back Directory | [Melting point ]
233-234 °C | [Boiling point ]
628.6±65.0 °C(Predicted) | [density ]
2.01 | [form ]
Solid | [pka]
12.60±0.70(Predicted) | [color ]
White to off-white | [InChI]
InChI=1/C10H12FN5O3/c11-5-7(18)4(1-17)19-10(5)16-3-15-6-8(12)13-2-14-9(6)16/h2-5,7,10,17-18H,1H2,(H2,12,13,14)/t4-,5+,7-,10-/s3 | [InChIKey]
ZGYYPTJWJBEXBC-VNCZOPGJNA-N | [SMILES]
[C@H]1(O)[C@H](F)[C@@H](O[C@@H]1CO)N1C2N=CN=C(N)C=2N=C1 |&1:0,2,4,6,r| |
| Hazard Information | Back Directory | [Uses]
2'-Deoxy-2'-fluoroarabinoadenosine is a nucleoside analogue, which exhibits anticancer activity against human immunodeficiency virus (HIV)[1]. | [References]
[1] Marquez VE, et al., 2',3'-Dideoxy-2'-fluoro-ara-A. An acid-stable purine nucleoside active against human immunodeficiency virus (HIV). Biochem Pharmacol. 1987 Sep 1;36(17):2719-22. DOI:10.1016/0006-2952(87)90254-1 |
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