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202284-84-2

202284-84-2 Structure

202284-84-2 Structure
IdentificationBack Directory
[Name]

Phosphoramidous acid, bis(1-methylethyl)-, 2-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-(methylamino)-2-[(methylamino)carbonyl]-3-oxopropyl 2-cyanoethyl ester (9CI)
[CAS]

202284-84-2
[Synonyms]

Phosphorylation amidite
Chemical phosphorylation amidite
Solid Chemical phosphorylation reagent II
3-(4,4'-Dimethoxytrityloxy)-2,2-dicarboxymethylamido]propyl-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite
Phosphoramidous acid, bis(1-methylethyl)-, 2-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-3-(methylamino)-2-[(methylamino)carbonyl]-3-oxopropyl 2-cyanoethyl ester (9CI)
[Molecular Formula]

C37H49N4O7P
[MOL File]

202284-84-2.mol
[Molecular Weight]

692.78
Chemical PropertiesBack Directory
[Boiling point ]

802.6±65.0 °C(Predicted)
[pka]

13.05±0.46(Predicted)
Hazard InformationBack Directory
[Description]

Phosphorylation amidite is a reagent for the synthesis of oligonucleotides possessing 5'-terminal phosphate residues.
[Uses]

Chemical phosphorylation amidite is a click chemical class ADC linker. Click chemistry has good biological orthogonality characteristics: biocompatible, fast and highly specific in the biological environment, and has great application potential in the binding between nucleic acids, lipids, proteins and other molecules[1].
[References]

[1] Zhang X, et al. Applications of azide-based bioorthogonal click chemistry in glycobiology. Molecules. 2013 Jun 19;18(6):7145-59. DOI:10.3390/molecules18067145
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