| Identification | Back Directory | [Name]
(R)-2-HYDROXY-4-METHYLPENTANOIC ACID | [CAS]
20312-37-2 | [Synonyms]
D-Leucic acid
(R)-Leucic acid
2-hydroxy-4-Methyl-
D-2-Hydroxyisocaproic acid
D-a-Hydroxyisocaproic acid
D-ALPHA-HYDROXYISOCAPROIC ACID
R-2-Hydroxy-4-methylvaleric acid
D-2-Hydroxy-4-methylpentanoic acid
(R)-2-HYDROXY-4-METHYLPENTANOIC ACID
(2R)-2-hydroxy-4-methyl-valeric acid
(2R)-2-hydroxy-4-methylpentanoic acid
Pentanoic acid, 2-hydroxy-4-methyl-, (2R)- | [Molecular Formula]
C6H12O3 | [MDL Number]
MFCD00211263 | [MOL File]
20312-37-2.mol | [Molecular Weight]
132.16 |
| Chemical Properties | Back Directory | [Melting point ]
76-80℃ | [Boiling point ]
251.3±13.0 °C(Predicted) | [density ]
1.097±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
3.86±0.21(Predicted) | [color ]
White to off-white | [InChI]
1S/C6H12O3/c1-4(2)3-5(7)6(8)9/h4-5,7H,3H2,1-2H3,(H,8,9)/t5-/m1/s1 | [InChIKey]
LVRFTAZAXQPQHI-RXMQYKEDSA-N | [SMILES]
CC(C)C[C@@H](O)C(O)=O | [LogP]
0.522 (est) |
| Hazard Information | Back Directory | [Uses]
(R)-Leucic acid is an amino acid metabolite[1]. | [Definition]
ChEBI: The (R)-enantiomer of 2-hydroxy-4-methylpentanoic acid. Found in patients with short-bowel syndrome (an inborn error of metabolism), and in maple syrup urine disease, MSUD. | [References]
[1] Buck, S. B., et al. Total Synthesis and Anti-Tubulin Activity of Epi-C3 Analogues of Cryptophycin-24. Journal of Medicinal Chemistry, 2004. 47(14), 3697–3699. |
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