| Identification | Back Directory | [Name]
Benzenesulfonamide, 4-hydroxy-N-[4-[5-[[(4-hydroxyphenyl)sulfonyl]amino]-2-benzoxazolyl]phenyl]- | [CAS]
2043687-46-1 | [Synonyms]
Benzenesulfonamide, 4-hydroxy-N-[4-[5-[[(4-hydroxyphenyl)sulfonyl]amino]-2-benzoxazolyl]phenyl]- | [Molecular Formula]
C25H19N3O7S2 | [MOL File]
2043687-46-1.mol | [Molecular Weight]
537.57 |
| Chemical Properties | Back Directory | [Boiling point ]
773.8±70.0 °C(predicted) | [density ]
1.581±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
7.41±0.10(predicted) |
| Hazard Information | Back Directory | [Uses]
PBZ1038 is a highly effective inhibitor of Gram-negative chaperone proteins, achieving its antibacterial effect by inhibiting GroES/GroEL[1]. | [References]
[1] Godek J, et al. Bis-sulfonamido-2-phenylbenzoxazoles Validate the GroES/EL Chaperone System as a Viable Antibiotic Target[J]. Journal of the American Chemical Society, 2024. DOI:10.1021/jacs.4c05057 |
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