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204386-76-5

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204386-76-5 Structure

204386-76-5 Structure
IdentificationBack Directory
[Name]

4-Oxazolidinecarboxamide, 5-methyl-N-[(1S)-2-[(2R)-2-methyl-1-pyrrolidinyl]-2-oxo-1-(4-thiazolylmethyl)ethyl]-2-oxo-, (4S,5S)-
[CAS]

204386-76-5
[Synonyms]

S0373
S-0373
S 0373
Rovatirelin
4-Oxazolidinecarboxamide, 5-methyl-N-[(1S)-2-[(2R)-2-methyl-1-pyrrolidinyl]-2-oxo-1-(4-thiazolylmethyl)ethyl]-2-oxo-, (4S,5S)-
[Molecular Formula]

C16H22N4O4S
[MDL Number]

MFCD33404550
[MOL File]

204386-76-5.mol
[Molecular Weight]

366.44
Chemical PropertiesBack Directory
[Boiling point ]

755.1±60.0 °C(Predicted)
[density ]

1.315±0.06 g/cm3(Predicted)
[pka]

11.03±0.60(Predicted)
Hazard InformationBack Directory
[Uses]

Rovatirelin is an orally active thyrotropin-releasing hormone (TRH) analog. Rovatirelin binds to the human TRH receptor with a Ki value of 702 nM. Rovatirelin can be used to study spinocerebellar degeneration (SCD) [1].
[References]

[1] Ijiro T, et al. Effect of rovatirelin, a novel thyrotropin-releasing hormone analog, on the central noradrenergic system. Eur J Pharmacol. 2015 Aug 15;761:413-22. DOI:10.1016/j.ejphar.2015.05.047
Spectrum DetailBack Directory
[Spectrum Detail]

4-Oxazolidinecarboxamide, 5-methyl-N-[(1S)-2-[(2R)-2-methyl-1-pyrrolidinyl]-2-oxo-1-(4-thiazolylmethyl)ethyl]-2-oxo-, (4S,5S)-(204386-76-5)1HNMR
204386-76-5 suppliers list
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Telephone: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: TargetMol Chemicals Inc.  
Telephone: 15002134094
Website: https://www.targetmol.cn/
Company Name: Shanghai Amole Biotechnology Co., Ltd.  
Telephone: 13370042665 18916960931
Website: www.amole.com.cn/
Company Name: Taizhou Chuanxu Pharmaceutical Technology Co., Ltd.  
Telephone: chuanxupharma@126.co
Website:
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