| Identification | Back Directory | [Name]
METHYL 3-NITROPROPIONATE 97 | [CAS]
20497-95-4 | [Synonyms]
Methyl 3-Nitropropanoate
Methyl 3-nitropropionate
METHYL 3-NITROPROPIONATE 97
METHYL 3-NITROPROPIONATE 97%
2,4,7-Tribromo methyl benzoate
Propanoic acid, 3-nitro-, methyl ester | [Molecular Formula]
C4H7NO4 | [MDL Number]
MFCD00012361 | [MOL File]
20497-95-4.mol | [Molecular Weight]
133.1 |
| Chemical Properties | Back Directory | [Boiling point ]
68 °C/1 mmHg(lit.) | [density ]
1.249 g/mL at 25 °C(lit.) | [refractive index ]
n20/D 1.4350(lit.) | [Fp ]
110 °C | [pka]
7.67±0.29(Predicted) |
| Hazard Information | Back Directory | [Uses]
Methyl 3-Nitropropanoate is used to nitroaldol additions, condensation reactions, and Michael additions involving the NO2-substituted
carbon; the α-carbonyl carbon in dilithionitronate enolates of the esters undergoes alkylations, double
alkylations, and aldol and Michael additions; elimination of HNO2 from the products gives α,β-
unsaturated esters with substituents in either the β- or the α-position, thus making the reagent a
synthetic equivalent of acrylate anions with d3 or d2 reactivity; precursor to nitrile oxide for [3 + 2]
cycloadditions; 3-nitropropanoyl chloride can be used for enolate acylation and five-membered ring
annulation.
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