| Identification | Back Directory | [Name]
L-Lysine, L-α-aspartyl-L-asparaginyl-L-α-aspartyl-L-tyrosyl-L-isoleucyl-L-isoleucyl-L-prolyl-L-leucyl-L-prolyl-L-α-aspartyl-L-prolyl- (9CI) | [CAS]
205173-94-0 | [Synonyms]
L-Lysine, L-α-aspartyl-L-asparaginyl-L-α-aspartyl-L-tyrosyl-L-isoleucyl-L-isoleucyl-L-prolyl-L-leucyl-L-prolyl-L-α-aspartyl-L-prolyl- (9CI) | [Molecular Formula]
C64H98N14O21 | [MOL File]
205173-94-0.mol | [Molecular Weight]
1399.54 |
| Chemical Properties | Back Directory | [Boiling point ]
1724.9±65.0 °C(Predicted) | [density ]
1.349±0.06 g/cm3(Predicted) | [pka]
3.60±0.21(Predicted) | [Sequence]
Asp-Asn-Asp-Tyr-Ile-Ile-Pro-Leu-Pro-Asp-Pro-Lys |
| Hazard Information | Back Directory | [Uses]
PDGFR Y1021 peptide (non-phosphorylation) is the non-phosphorylated fragment of platelet-derived growth factor receptor (PDGFR). PDGFR Y1021 peptide (non-phosphorylation) blocks the PLCγ association to PDGFR through PLCγSH2 domain, and thus inhibits mitogenic response[1]. | [References]
[1] Valius M, et al., Tyrosines 1021 and 1009 are phosphorylation sites in the carboxy terminus of the platelet-derived growth factor receptor beta subunit and are required for binding of phospholipase C gamma and a 64-kilodalton protein, respectively. Mol Cell Biol. 1993 Jan;13(1):133-43. DOI:10.1128/mcb.13.1.133-143.1993 |
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