| Identification | Back Directory | [Name]
PDGFR Tyrosine Kinase Inhibitor III | [CAS]
205254-94-0 | [Synonyms]
PDGFR Tyrosine Kinase Inhibitor III | [Molecular Formula]
C27H27N5O4 | [MDL Number]
MFCD09037549 | [MOL File]
205254-94-0.mol | [Molecular Weight]
485.53 |
| Chemical Properties | Back Directory | [Melting point ]
218-219 °C(Solv: chloroform (67-66-3)) | [Boiling point ]
713.7±60.0 °C(Predicted) | [density ]
1.310±0.06 g/cm3(Predicted) | [solubility ]
DMSO: Sparingly soluble: 1-10 mg/ml
Ethanol: Slightly soluble: 0.1-1 mg/ml | [form ]
Solid | [pka]
13.18±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
IUN54940, also known as PDGFR Tyrosine Kinase Inhibitor III, is a PDGFR inhibitor. | [Uses]
PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III), a multikinase inhibitor, inhibits PDGFR, EGFR, FGFR, PKA, and PKC, respectively. PDGFR Tyrosine Kinase Inhibitor III can be used for the research of amyotrophic lateral sclerosis[1]. | [Definition]
ChEBI: PDGF receptor tyrosine kinase inhibitor III is an N-arylpiperazine that is piperazine in which the hydrogen attached to the nitrogen at position 1 is replaced by a (4-phenoxyphenyl)aminocarbonyl group, while the hydrogen attached to the nitrogen at position 4 is replaced by a 6,7-dimethoxyquinazolin-4-yl group. It is an inhibitor of tyrosine kinases FLT3, PDGFR and KIT. It has a role as an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. It is a N-arylpiperazine, a N-carbamoylpiperazine, an aromatic ether, a member of phenylureas, a member of quinazolines and a tertiary amino compound. | [References]
[1] Young-Min Lee. Compositions and methods for zika virus characterization and vaccine development. WO2019204654A1. |
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InvivoChem
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13549236410 |
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https://www.invivochem.cn/ |
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