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20535-16-4

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20535-16-4 Structure

20535-16-4 Structure
IdentificationBack Directory
[Name]

9-(3'-fluoro-3'-deoxyxylofuranosyl)adenine
[CAS]

20535-16-4
[Synonyms]

3'-Deoxy-3'-fluoro-xyloadenosine
9-(3'-fluoro-3'-deoxyxylofuranosyl)adenine
9H-Purin-6-amine, 9-(3-deoxy-3-fluoro-β-D-xylofuranosyl)-
3’-Deoxy-3’-fluoro-xyloadenosine, 9-(3-Deoxy-3-fluoro-beta-D-xylofuranosyl)adenine
(2R,3S,4R,5R)-2-(6-amino-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol
[Molecular Formula]

C10H12FN5O3
[MOL File]

20535-16-4.mol
[Molecular Weight]

269.24
Chemical PropertiesBack Directory
[Boiling point ]

628.6±65.0 °C(Predicted)
[density ]

2.01±0.1 g/cm3(Predicted)
[pka]

12.45±0.70(Predicted)
Hazard InformationBack Directory
[Uses]

3’-Deoxy-3’-fluoro-xyloadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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