| Identification | Back Directory | [Name]
m-PEG9-phosphonic acid | [CAS]
2055016-25-4 | [Synonyms]
m-PEG9-phosphonic acid
Phosphonic acid, P-3,6,9,12,15,18,21,24,27-nonaoxaoctacos-1-yl- | [Molecular Formula]
C19H41O12P | [MDL Number]
MFCD28505502 | [MOL File]
2055016-25-4.mol | [Molecular Weight]
492.5 |
| Chemical Properties | Back Directory | [Boiling point ]
582.5±60.0 °C(Predicted) | [density ]
1.176±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Water, DMSO, DCM, DMF | [form ]
Solid | [pka]
2.14±0.10(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Description]
m-PEG9-phosphonic acid ethyl ester is a PEG chain linker. The hydrophilic PEG linkers increase the water solubility of compound in aqueous media. Longer PEG chains have better water solubility properties relative to shorter PEG chains. | [Uses]
m-PEG9-phosphonic acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. | [IC 50]
PEGs | [References]
[1] Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238. DOI:10.1016/j.apsb.2019.08.001 |
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