ChemicalBook--->CAS DataBase List--->2055022-06-3

2055022-06-3

2055022-06-3 Structure

2055022-06-3 Structure
IdentificationBack Directory
[Name]

TCO-PEG12-DBCO
[CAS]

2055022-06-3
[Synonyms]

TCO-PEG12-DBCO
DBCO-PEG12-TCO
[Molecular Formula]

C54H81N3O16
[MDL Number]

MFCD28334562
[MOL File]

2055022-06-3.mol
[Molecular Weight]

1028.23
Chemical PropertiesBack Directory
[Boiling point ]

1038.7±65.0 °C(Predicted)
[density ]

1.20±0.1 g/cm3(Predicted)
[solubility ]

Soluble in DMSO, DCM, DMF
[pka]

11.95±0.46(Predicted)
Hazard InformationBack Directory
[Description]

TCO-PEG12-DBCO is a long chain PEGreagent containing a TCO and a DBCO moiety. TCO group specifically and efficiently reacts with terrahydrazine under mild condition. DBCO is very reactive toward Azide through click chemistry, the PEG spacer increases the aqueous solubility of the reagent.
[Uses]

DBCO-PEG12-TCO cantains a TCO and a DBCO moiety. TCO group can specifically react with terrahydrazine. DBCO-PEG12-TCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. DBCO-PEG12-TCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
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