| Identification | Back Directory | [Name]
m-PEG3-S-PEG3-t-butyl ester | [CAS]
2055040-96-3 | [Synonyms]
m-PEG3-S-PEG3-Boc
m-PEG3-S-PEG3-t-butyl ester
4,7,10,16,19,22-Hexaoxa-13-thiatricosanoic acid, 1,1-dimethylethyl ester | [Molecular Formula]
C20H40O8S | [MDL Number]
MFCD29918259 | [MOL File]
2055040-96-3.mol | [Molecular Weight]
440.59 |
| Hazard Information | Back Directory | [Description]
m-PEG3-S-PEG3-t-butyl ester is a PEG linker containing a t-butyl ester moiety. The t-butyl ester can be removed under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media. | [Uses]
m-PEG3-S-PEG3-Boc is a PEG- and Alkyl/ether -based PROTAC linker can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs; Alkyl/ether | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005 |
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