Chemical Properties | Back Directory | [Boiling point ]
916.2±65.0 °C(Predicted) | [density ]
1.202±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Water, DMSO, DMF | [form ]
Solid | [pka]
3.54±0.10(Predicted) | [color ]
Light yellow to light brown |
Hazard Information | Back Directory | [Description]
N-(Propargyl-PEG4)-biocytin is a biotin PEG reagent that is reactive with azide containing molecule via click chemistry. | [Uses]
N-(Propargyl-PEG4)-biocytin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Propargyl-PEG4)-biocytin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
|
|