| Identification | Back Directory | [Name]
1-MYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | [CAS]
20559-16-4 | [Synonyms]
M-LysoPC
14:0 LYSO PC
LysoPC(14:0/0:0)
LYSOLECITHIN, MYRISTOYL
L-A-lysophosphatidylcholine
Lysolecithin, tetradecanoyl
L-γ-Myristoyl-α-lysolecithin
L-g-Myristoyl-a-lysolecithin
1-myristoylglycerophosphocholine
L-GAMMA-MYRISTOYL-ALPHA-LYSOLECITHIN
Myristoyl L-α-lysophosphatidylcholine
1-Myristoyl-2-hydroxy-sn-glycero-3-PC
1-MYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
3-SN-LYSOPHOSPHATIDYLCHOLINE, 1-MYRISTOYL
L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, MYRISTOYL
1-Myristoyl-sn-glycero-3-phosphatidylcholine
1-myristoyl-sn-glycero-3-phosphocholine(M-LysoPC)
1-MYRISTOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHOCHOLINE
1-MYRISTOYL-2-HYDROXY-SN-GLYCERO-3-PHOSPHATIDYLCHOLINE
1-Myristoyl-1-acyl-2-hydroxy-sn-glycero-3-phosphatidylcholine
(2R)-2-hydroxy-3-tetradecanoyloxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
(R)-2-Hydroxy-3-(tetradecanoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
Myristoyl Lyso-phosphocholine ,1-myristoyl-2-hydroxy-sn-glycero-3-phosphocholine
(R)-4,7-dihydroxy-N,N,N-trimethyl-10-oxo-3,5,9-Trioxa-4 phosphatricosan-1-aminium 4-oxide inner salt
Antispasmodic,Endogenous Metabolite,LysoPC(14:0/0:0),lysophospholipid,Inhibitor,inhibit,phosphorylcholine
3-sn-Lysophosphatidylcholine, 1-myristoyl, L-γ-Myristoyl-α-lysolecithin, Lysolecithin, tetradecanoyl, Myristoyl L-α-lysophosphatidylcholine | [Molecular Formula]
C22H46NO7P | [MDL Number]
MFCD00036902 | [MOL File]
20559-16-4.mol | [Molecular Weight]
467.58 |
| Chemical Properties | Back Directory | [Melting point ]
>142°C (dec.) | [storage temp. ]
−20°C
| [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
White to Off-White | [InChI]
InChI=1/C22H46NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-22(25)28-19-21(24)20-30-31(26,27)29-18-17-23(2,3)4/h21,24H,5-20H2,1-4H3/t21-/s3 | [InChIKey]
VXUOFDJKYGDUJI-DLINEHSKNA-N | [SMILES]
P([O-])(=O)(OCC[N+](C)(C)C)OC[C@H](O)COC(=O)CCCCCCCCCCCCC |&1:12,r| |
| Safety Data | Back Directory | [WGK Germany ]
3
| [F ]
10 | [Hazard Classifications]
Acute Tox. 3 Inhalation
Acute Tox. 4 Oral
Aquatic Chronic 3
Carc. 2
Eye Irrit. 2
Repr. 2
Skin Irrit. 2
STOT RE 1
STOT SE 3 |
| Hazard Information | Back Directory | [Description]
1-MYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE is a lysophospholipid (LyP), which is a monoglycerophospholipid in which the phosphorylcholine moiety occupies the glycerol substitution site. LysoPC(14:0/0:0) has a potent antispasmodic effect. | [Physical properties]
1-MYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE is a Solid,it can insoluble in water. | [Uses]
1-Myristoyl-sn-glycero-3-phosphocholine is a derivative of sn-Glycero-3-phosphocholine (G598700) and can be used as a biomarker in biological studies. | [Definition]
ChEBI: 1-myristoyl-sn-glycero-3-phosphocholine is a lysophosphatidylcholine 14:0 in which the acyl group specified is myristoyl. The major species at pH 7.3. It is a lysophosphatidylcholine 14:0, a 1-O-acyl-sn-glycero-3-phosphocholine and a tetradecanoate ester. | [in vivo]
Of the saturated fatty acid-containing L-α-lysolecithins (LPC), palmitoyl-LPC shows the strongest antispasmodic effect against acetylcholine- or histamine-induced guinea pig ileum contraction; the order of potency of the others is (LysoPC(14:0/0:0)) myristoyl- > stearoyl-, lauroyl- > decanoyl-LPC. Incorporation of a cis-double bond into the C18 fatty acid chain of LPC resulted in a slight decrease of the antispasmodic effect[1]. | [IC 50]
Human Endogenous Metabolite | [storage]
Store at -20°C |
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