| Identification | Back Directory | [Name]
AZD4573 | [CAS]
2057509-72-3 | [Synonyms]
AZD4573
AZD-4573;AZD4573;AZD 4573
(1S,3R)-N-(5-chloro-4-{5,5-dimethyl-4H,5H,6H-pyrrolo[1,2-b]pyrazol-3-yl}pyridin-2-yl)-3-acetamidocyclohexane-1-carboxamide
(1S,3R)-3-acetamido-N-[5-chloro-4-(5,5-dimethyl-4,6-dihydropyrrolo[1,2-b]pyrazol-3-yl)pyridin-2-yl]cyclohexane-1-carboxamide
(1S,3R)-3-acetamido-N-(5-chloro-4-(5,5-dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)pyridin-2-yl)cyclohexane-1-carboxamide
Cyclohexanecarboxamide, 3-(acetylamino)-N-[5-chloro-4-(5,6-dihydro-5,5-dimethyl-4H-pyrrolo[1,2-b]pyrazol-3-yl)-2-pyridinyl]-, (1S,3R)- | [Molecular Formula]
C22H28ClN5O2 | [MDL Number]
MFCD31657407 | [MOL File]
2057509-72-3.mol | [Molecular Weight]
429.94 |
| Chemical Properties | Back Directory | [Boiling point ]
692.8±55.0 °C(Predicted) | [density ]
1.39±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : ≥ 125 mg/mL (290.74 mM) | [form ]
Solid | [pka]
12.28±0.40(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
AZD4573, is a CDK9 inhibitor. | [in vivo]
AZD4573 exhibits a short half-life in multiple species (less than one hour in rat, dog and monkey) and good solubility for intravenous administration[1]. | [IC 50]
CDK9: 4 nM (IC50) |
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