| Identification | Back Directory | [Name]
MMB-4 | [CAS]
2058-89-1 | [Synonyms]
MMB-4
MMB-4 >=98% (HPLC)
1,1′-Methylenebis[4-[(hydroxyimino)methyl]-pyridinium dibromide | [Molecular Formula]
C13H14Br2N4O2 | [MDL Number]
MFCD01691018 | [MOL File]
2058-89-1.mol | [Molecular Weight]
418.084 |
| Chemical Properties | Back Directory | [Melting point ]
235.0 °C | [storage temp. ]
2-8°C | [solubility ]
H2O: soluble20mg/mL, clear | [form ]
powder | [color ]
light yellow to light brown | [Water Solubility ]
H2O: 20mg/mL, clear | [InChI]
1S/C13H12N4O2.2BrH/c18-14-9-12-1-5-16(6-2-12)11-17-7-3-13(4-8-17)10-15-19;;/h1-10H,11H2;2*1H | [InChIKey]
ZKQNRRLCBJUEBC-UHFFFAOYSA-N | [SMILES]
O/N=C/C1=CC=[N+](C[N+]2=CC=C(/C=N\O)C=C2)C=C1.[Br-].[Br-] |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H302 | [Precautionary statements ]
P264-P270-P301+P312-P330-P501 | [Hazard Codes ]
Xn | [Risk Statements ]
22 | [WGK Germany ]
3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral | [Toxicity]
mouse,LD50,intramuscular,448mg/kg (448mg/kg),BEHAVIORAL: TREMORLUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATIONBEHAVIORAL: ATAXIA,National Technical Information Service. Vol. AD-A131-940, |
| Hazard Information | Back Directory | [Uses]
MMB-4 is an oxime that can reactivate cholinesterases that have been inactivated by exposure to organophosphates such as Sarin or Soman[1]. | [Biological Activity]
MMB-4 is also called as 1,1μ-Methylenebis{4-[(hydroxyimino)methyl]pyridinium) dichloride. It serves as a promising antidote for organophosphate poisoning.''MMB-4 is an oxime th at can reactivate cholinesterases th at have been inactivated by exposure to organophosphates such as sarin or soman. Administration of MMB-4 and atropine normalizes many respiratory parameters in guinea pigs following soman inhalation. | [References]
[1] Paul M Lundy, et al. Comparative protective effects of HI-6 and MMB-4 against organophosphorous nerve agent poisoning. Review Toxicology. 2011 Jul 29;285(3):90-6. DOI:10.1016/j.tox.2011.04.006 |
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| Company Name: |
Energy Chemical
|
| Telephone: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
TargetMol
|
| Telephone: |
400-821-0310 15002144251 |
| Website: |
www.targetmol.cn/ |
|