| Identification | Back Directory | [Name]
6-Bromo-4-hydroxy-pyrazolo[1,5-a]pyridine-3-carbonitrile | [CAS]
2068065-16-5 | [Synonyms]
6-Bromo-4-hydroxy-pyrazolo[1,5-a]pyridine-3-carbonitrile
Pyrazolo[1,5-a]pyridine-3-carbonitrile, 6-bromo-4-hydroxy- | [Molecular Formula]
C8H4BrN3O | [MDL Number]
MFCD34182974 | [MOL File]
2068065-16-5.mol | [Molecular Weight]
238.04 |
| Chemical Properties | Back Directory | [density ]
1.88±0.1 g/cm3(Predicted) | [pka]
6.41±0.30(Predicted) | [InChI]
InChI=1S/C8H4BrN3O/c9-6-1-7(13)8-5(2-10)3-11-12(8)4-6/h1,3-4,13H | [InChIKey]
IFUVDUFAFVWZOT-UHFFFAOYSA-N | [SMILES]
C12=C(C#N)C=NN1C=C(Br)C=C2O |
| Hazard Information | Back Directory | [Uses]
6-Bromo-4-hydroxy-pyrazolo[1,5-a]pyridine-3-carbonitrile is a pharmaceutical intermediate used in the preparation of Selpercatinib, an FDA-approved drug for the treatment of RET-positive advanced non-small cell lung cancer (NSCLC), thyroid cancer and certain other cancers |
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