| Identification | Back Directory | [Name]
PE(18：2(9Z,12Z)/18:2(9Z,12Z)) | [CAS]
20707-71-5 | [Synonyms]
PE(18：2(9Z,12Z)/18:2(9Z,12Z))
9,12-Octadecadienoic acid (9Z,12Z)-, 1,1'-[(1R)-1-[[[(2-aminoethoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl] ester | [Molecular Formula]
C41H74NO8P | [MOL File]
20707-71-5.mol | [Molecular Weight]
740.02 |
| Chemical Properties | Back Directory | [Boiling point ]
758.4±70.0 °C(Predicted) | [density ]
1.020±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
liquid | [pka]
1.17±0.50(Predicted) |
| Hazard Information | Back Directory | [Uses]
1,2-Dilinoleoyl-sn-glycero-3-phosphoethanolamine is used in the compositions including cationic and neutral lipids for transfecting mRNA into a cell for therapeutic applications for cancer and viral infections. | [Definition]
ChEBI: 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine is a 1,2-diacyl-sn-glycero-3-phosphoethanolamine in which the acyl substituent both at positions 1 and 2 is specified as (9Z,12Z)-octadecadienoyl respectively. It has a role as a mouse metabolite. It is functionally related to a linoleic acid. It is a conjugate acid of a 1,2-dilinoleoyl-sn-glycero-3-phosphoethanolamine zwitterion. | [Biological Activity]
Phosphatidylethanolamine (PE) functions as to provide rigidity to the cell membranes via hexagonal phase structures which promote tight packing of the membrane bilayer formed by phosphatidylcholine. It is also involved in the conversion of prions from the non-toxic to toxic conformation. PE also initiates the autophagosome formation by attaching covalently to the autophagy Atg8 protein. |
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| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
| Company Name: |
Creative Enzymes
|
| Tel: |
1-516-855-7709 |
| Website: |
www.creative-enzymes.com |
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