| Identification | Back Directory | [Name]
4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU& | [CAS]
207233-90-7 | [Synonyms]
4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-D
4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU&
Disodium 4,4′-diisothiocyanatostilbene-2,2′-disulfonate
DIDS, Disodium 4,4μ-diisothiocyanatostilbene-2,2μ-disulfonate
Disodium 4,4'-diisothiocyanato-2,2'-stilbenedisulphonate hydrate
4,4''-DIISOTHIOCYANATOSTILBENE-2,2''-DISULPHONIC ACID DISODIUM SALT
disodium 2,2'-(E)-ethene-1,2-diylbis(5-isothiocyanatobenzenesulfonate)
4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid disodium salt hydrate
4，4'-Diisothiocyanatostilbene-2，2'-disulfonic acid disodium salt hydrate
4,4'-Diisothiocyanatostilbene-2,2'-disulphonic acid disodium salt hydrate
4,4μ-Diisothiocyanato-2,2μ-stilbenedisulfonic acid hydrate disodium salt
4,4μ-Diisothiocyanatostilbene-2,2μ-disulfonic acid hydrate disodium salt
4,4'-DIISOTHIOCYANATO-2,2'-STILBENEDISUL -FONIC ACID, DI-NA SALT XH2O TECH., 90%
4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid disodium salt hydrate >=80% (elemental analysis), powder
DisodiuM 4,4'-diisothiocyanatostilbene-2,2'-disulfonate, 4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid disodiuM salt hydrate | [Molecular Formula]
C16H13N2NaO7S4 | [MDL Number]
MFCD00009638 | [MOL File]
207233-90-7.mol | [Molecular Weight]
496.52 |
| Hazard Information | Back Directory | [Uses]
4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid disodium salt hydrate has been used:
- as band3 protein inhibitor in rabbits(19)
- for the inhibition of bicarbonate transporters in brain slice tissue(20)
- as HCO3-/Cl- exchanger (anion exchanger) in embryos(21)
| [reaction suitability]
reagent type: cross-linking reagent | [Biochem/physiol Actions]
4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid is an anionic alkylating agent containing isothiocyanate residue. It is a negatively charged homobifunctional cross-linking reagent. 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid is a specific inhibitor of cellular anion permeability used in cell transport studies. The isothiocyanate groups react with primary amines at pH 9.0-10.0. 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid alkylates lysine residues and inhibits apoptosis indirectly by targeting membrane based anion transporters.In addition, it also inhibits calcium transport in vesicles. |
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