207801-27-2

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207801-27-2 Structure

Identification	Back Directory
[Name] YOHIMBINIC ACID MONOHYDRATE 99
[CAS] 207801-27-2
[Synonyms] YOHIMBINIC ACID MONOHYDRATE 99
[Molecular Formula] C20H24N2O3.H2O
[MDL Number] MFCD00167087
[MOL File] 207801-27-2.mol
[Molecular Weight] 358.435

Safety Data	Back Directory
[Symbol(GHS) ] GHS06
[Signal word ] Danger
[Hazard statements ] H331-H301-H311
[Precautionary statements ] P261-P271-P304+P340-P311-P321-P403+P233-P405-P501-P264-P270-P301+P310-P321-P330-P405-P501-P280-P302+P352-P312-P322-P361-P363-P405-P501
[Hazard Codes ] T
[Risk Statements ] 23/24/25
[Safety Statements ] 26-28-36/37/39-45
[RIDADR ] UN 1544 6.1/PG 3
[WGK Germany ] 3

Hazard Information	Back Directory
[Uses] Yohimbic acid hydrate is an amphoteric demethylated derivative of Yohimbine (HY-12715). Yohimbic acid hydrate exhibits vasodilatory action. Yohimbic acid hydrate also can be used for the research of osteoarthritis (OA)[1][2][3].
[References] [1] HAMET R. Demonstration of the direct vasodilatory action of yohimbic acid and Py-tetrahydroquinoline. C R Hebd Seances Acad Sci. 1960 Jun 27;250:4473-5. PMID:13854468 [2] HAMET R. Sympatholytic activity and toxicity of an amphoteric demethylated derivative of yohimbine: yohimbic acid. C R Hebd Seances Acad Sci. 1951 Oct 29;233(18):1069-71. PMID:14896545 [3] Wang S, et, al. Significantly dysregulated genes in osteoarthritic labrum cells identified through gene expression profiling. Mol Med Rep. 2019 Aug; 20(2): 1716-1724. DOI:10.3892/mmr.2019.10389

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