ChemicalBook--->CAS DataBase List--->20788-07-2

20788-07-2

20788-07-2 Structure

20788-07-2 Structure
IdentificationBack Directory
[Name]

Resorantel
[CAS]

20788-07-2
[Synonyms]

RESORANTEL
Pesorantelum
N-(4-Bromophenyl)-2,6-dihydroxybenzamide
Benzamide, N-(4-bromophenyl)-2,6-dihydroxy-
[EINECS(EC#)]

244-040-9
[Molecular Formula]

C13H10BrNO3
[MDL Number]

MFCD00864511
[MOL File]

20788-07-2.mol
[Molecular Weight]

308.13
Chemical PropertiesBack Directory
[Melting point ]

229-230°; mp 183-186° (LeMaire)
[Boiling point ]

391.1±42.0 °C(Predicted)
[density ]

1.699±0.06 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,2-8°C
[solubility ]

DMSO : 250 mg/mL (811.35 mM; Need ultrasonic)
[form ]

Solid
[pka]

7.62±0.35(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]

GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07
[Signal word ]

Danger
[Hazard statements ]

H302-H315-H314
[Precautionary statements ]

P260-P264-P270-P280-P301+P330+P331-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P310-P332+P313-P362-P405-P501
Hazard InformationBack Directory
[Uses]

Resorantel is an anthelmintic[1]. Resorantel is used in the research of paramphistomiasis in cattle and sheep and has also been used for the research of G. aegypticus[2].
[in vivo]

Resorantel (65 mg/kg, a single oral dose) possesses efficacy against paramphistomiasis in naturally infected sheep[1].

Animal Model:Five flocks of sheep in different villages of Haryana[1].
Dosage:65 mg/kg.
Administration:A single oral dose.
Result:None of the treated sheep died of enteric paramphistomiasis. The clinical signs disappeared within 2 to 3 days of the treatment and their appetite and general condition improved. No ill effects of the drug were noticed. Of the untreated sheep, 35 % died with a range of 24-52 % in the different flocks. Many of the other untreated sheep continued to exhibit clinical signs of paramphistomiasis.
[storage]

Store at -20°C
[References]

[1] R P Gupta, et al. Efficacy of resorantel against paramphistomiasis in naturally infected sheep. Trop Anim Health Prod. 1981 Feb;13(1):35-6. DOI:10.1007/BF02237884
[2] Swan GE. The pharmacology of halogenated salicylanilides and their anthelmintic use in animals. J S Afr Vet Assoc. 1999;70(2):61-70. DOI:10.4102/jsava.v70i2.756
Spectrum DetailBack Directory
[Spectrum Detail]

Resorantel(20788-07-2)1HNMR
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